ACE inhibitors relax blood vessels, and decrease blood volumewhich lowers blood pressure and decreases oxygen demand from the heart. Benazeprilbrand name Lotensin Novartisis an ACE inhibitor used primarily in treatment of hypertensioncongestive heart failureand heart attacksand also in preventing the renal and retinal complications of diabetes.
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Overall, there were no major differences in side effects between patients taking Lotensin or the placebo. In a nutshell, concerns centered on blood levels of potassium and creatininewaste products that are excreted by the kidneys. The key question was whether damaged kidneys would worsen if patients took ACE inhibitors. Under the brand names Fortekor Novartis and VetACE Jurox Animal Health[ citation needed ] benazepril hydrochloride is used to treat congestive heart failure in dogs   and chronic renal failure in dogs and cats.
Gemopatrilat Ilepatril Omapatrilat Sampatrilat. The most common side effects patients experience are a headache or a chronic cough.
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Captopril Rentiapril Zofenopril Dicarboxylate-containing: This page was last edited on 5 Septemberat Retrieved 2 April Retrieved from " https: Views Read Edit View history. Benazepril is a prodrug which is metabolized by the liver into its active form benazeprilat via cleavage of the drug's ester group.
New Insights Into Mechanisms and Management".
According to coverage of the study on WebMD: Patients with advanced renal insufficiency taking benazepril show "substantial" kidney benefits.
They inhibit angiotensin-converting enzymewhich is part of the renin—angiotensin—aldosterone system.