Lamotrigine cims


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If you log out, you will be required to enter your username and password the next time you visit. Inhibits release of excitatory amino acid glutamate and inhibits voltage-sensitive sodium channel, which stabilizes neuronal membranes.


Share cases and questions with Physicians on Medscape consult. May interfere with the assay used in some rapid urine drug screens, which can result in false-positive readings, particularly for phencyclidine PCP ; use a more specific analytical method to confirm a positive result. Thus, the drug should be discontinued at the first sign of rash unless the rash is clearly not drug related.

Adding plans allows you to compare formulary status to other drugs in the same class.

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Need to modify dosage if adding or discontinuing hepatic enzyme-inducing anticonvulsant drugs or valproic acid. Closely monitor infant and measure infant serum level for toxicity if concerns arise; discontinue with lamotrigine toxicity.

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This restriction typically requires that certain criteria be met prior to approval for the prescription. Increased risk of hematologic effects eg, neutropenia, anemia, leukopenia, thrombocytopenia, aplastic anemia in patients with previous history of adverse hematologicreactions to any drug.

With valproic acid age yr Initial: Multiorgan hypersensitivity reactions, also known as drug reaction with eosinophilia and systemic symptoms DRESShave been reported, with possible multiorgan failure see Black Box Warning. This website uses cookies to deliver its services as described in our Cookie Policy. Print with Office Info. Controlled studies in pregnant women show no evidence of fetal risk. The above information is provided for general informational and educational purposes only.

Significant - Monitor Closely. This drug is available at a higher level co-pay. Metabolism Hepatic and renal through glucuronidation Metabolites: Step Therapy Drugs that have step therapy associated with each prescription.

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Contraindications Hypersensitivity to any component of formulation. Indicated for maintenance treatment of bipolar I disorder to delay the time to occurrence of mood episodes depression, mania, hypomania, mixed episodes in patients treated for acute mood episodes with standard therapy. Prior Authorization Drugs that require prior authorization.

This restriction requires that specific clinical criteria be met prior to the approval of the prescription. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.

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